Tsi mawan ni hpe tsi lajang ai hta ahkyak ai carrier langai hku nna, gelatin capsules ni a ngang grin ai lam ni gaw, tsi hpe shinggyin tawn da ai, htawt sit ai, hte jahtum na akyu rawng ai lam ni hte hkrak matut mahkai nga ai. Stability ngu ai gaw, capsule a shi a hkum hkrang hkrang hte chemical atsam marai ni hpe shinggyin tawn da ai aten hta sha n-ga, grup yin masa amyu myu a npu e, nbung katsi ai, katsi ai, nhtoi zawn re ai lam ni hpe hkam sharang lu ai atsam hpe tsun mayu ai. Gelatin empty capsules ni a ngang grin ai atsam ningja ni hpe atsawm chye na ai gaw, nanghpam lu sha ai lam hpe hkam la lu na matu hte n-gun hpe jat ya lu na matu ahkyak ai lam kaba rai nga ai.
Hkum hkrang hte seng ai lam: Form hte jak rung ni hpe sin ai
Gelatin capsules ni a hkum hkrang n-gun gaw madung hku nna shanhte a hkum hkrang n-gun hte jak rung n-gun atsam hta dan dawng nga ai. Htap htuk ai nbung laru hte hka lim ai masa ni hta, capsules ni gaw, n-gun n rawng ai, n-gun n rawng ai, n-gun n rawng ai zawn re ai mabyin masa ni hpe koi nna, grup yin hpe atsawm sha, n-gun rawng ai, n-gun ja ai lam ni hpe n-gun jaw ra ai. Capsules ni a hkum hkrang ngang grin ai lam gaw, gelatin source, galaw shapraw ai lam, shinggyin tawn ai masa ni lawm ai lam ni hpe kahkyin gumdin ai lam ni a majaw byin pru wa ai. Ga shadawn, Type A gelatin (acid{3}} n-gun rawng ai) hte Type B gelatin (alkali-p) ni gaw molecular structure hte hygroscopicity hta shai hkat ai majaw, n bung ai hka lim ai madang ni a npu hta n bung ai ngang grin ai lam ni hpe galaw lu wa ai. Dai hta n-ga, empty capsule a hka n-gun gaw, shi a hkum hkrang hpe hkra machyi shangun ai madung lam langai rai nna, 12% hte 15% lapran hta, laksan hku nna hkang lu ai. Grai tsaw ai (sh) grai n law ai madang ni gaw, n-gun n rawng ai capsule hpe n-gun n rawng ai (sh) n-gun n rawng ai hku byin shangun nna, shi a bungli hpe hkra machyi shangun ai.
Chemical Stability: Compposition hte htuk manu ai lam hpe kam hpa ai lam
Chemical stability ngu ai gaw, gelatin capsules ni a chemical hten za ai lam hpe ninghkap lu ai atsam (sh) n kaja ai akyu ni hpe hkam sharang lu ai atsam hpe tsun mayu ai. Shingra tara hku nna, gelatin a molecular chains ni gaw, nbung katsi ai, katsi ai, shing nrai, n-gun n law ai aten hta, hydrolysis galaw mai ai. Chemical n-gun hpe jat ya na matu, galaw shapraw ai ni gaw, preservatives hte antioxidants zawn re ai excipient ni hpe law law lang jat bang ma ai. Grau nna, empty capsules ni gaw shi shinggrup da ai tsi hte kaja ai htuk manu ai lam hpe madun dan ra ai. Tsi mawan nkau mi (ga shadawn, aldehydes, n-gun ja ai acid, shing nrai, npawt nhpang ni) gaw gelatin hta amino acid ni hte bai htang chye ai majaw, cross{6}}linking (sh) hten za mat ai majaw, tsi hpe shapraw ai hte bioavailability hpe hkra machyi shangun chye ai. Dai majaw, compatibility chyam dinglik ai lam gaw, formulation galaw ai lam hta ahkyak ai daw langai rai nga ai.
Hkringmang daju
Hkringmang daju a grup yin hpe galai shai lu ai atsam gaw, capsule langai a ngang grin ai lam hpe shadawn shadang langai mi rai nga ai. Mungkan madang hku yu yang, capsule ni gaw 25℃/60% RH (sh) 40℃/75% RH masa ni a npu hta ngang grin ai lam hpe chyam dinglik ai lam galaw ai. High{7}} manu dan ai capsules ni gaw, grai sawng ai makau grup yin ni a npu e, hkum hkrang hkrang hte hka lim ai lam hpe kaja ai hku tawn da lu ra ai, hka hpe hkap la ai (sh) sum mat ai majaw byin pru wa ai bungli galaw ai lam hpe hkra machyi shangun ai. Dai hta n-ga, n-gun n rawng ai capsule (ga shadawn, blister packs, bottle) ni a packaging hkrang mung shi a grup yin hpe galai shai lu ai atsam hpe grai hkra machyi shangun ai. Htap htuk ai packaging gaw shinggan na hka hte oxygen hpe hkrak hkra pat kau ya lu ai majaw, capsule a ngang grin ai asak hkrung lam hpe jat ya lu ai.
Stability hpe jep joi ai lam hte Quality hpe hkang ai lam
Gelatin capsules ni a ngang grin ai lam hpe kam na matu, tsi company ni gaw, n-gun rawng ai hkang zing ai ladat hpe hpaw ra ai, dai hta raw material jep joi ai lam,-} hpe yu reng ai lam, hte ngut sai arai ni hpe ngang grin ai lam hpe chyam dinglik ai lam ni hta lawm ai. Masha law malawng jep joi ai lam ni hta, myi hte mu lu ai hku jep joi ai lam, hkum hkrang n bung ai lam hpe chyam dinglik ai lam, garan ginhka ai aten hpe garan ginhka ai aten hpe dawdan ai lam, jak hte n-gun n-gun hpe chyam dinglik ai lam ni lawm ai. Systematic stability sawk sagawn ai lam ni hku nna, capsule ni a shinggyin tawn da ai masa hte shelf life hpe dawdan lu ai, dai tsi hpe shim lum ai hte hkrak hkra jai lang lu na matu hpaji masa hpe jaw ya lu ai.
Daw dan lam
The stability characteristics oflaetin capsulesgaw tsi hpaji hpe hkang zing ai lam hta ahkyak ai matut mahkai lam rai nga ai, hkum hkrang, tsi mawan, grup yin hpe galai shai lu ai atsam zawn re ai lam law law hpe lawm ai. Hpaji masa hte tsi hpaji masa ni matut manoi rawt jat wa ai hte, capsule ni a ngang grin ai lam hpe gelatin tsi ni hpe grau kaja hkra galaw ai, galaw shapraw ai lam ni hpe grau kaja hkra galaw ai, hte n-gun ja ai packaging hpaji ni hpe gram lajang ai hku nna grau nna jat wa lu ai, dai hku nna tsi mawan hkyen lajang ai lam ni hpe gyin shalat nna jai lang na matu grau kam hpa mai ai madi shadaw lam hpe jaw ya lu ai. Htawm hpang de, tinang a tsi hpaji hte tsi mawan nnan ni hpe garan gachyan ai ladat ni hpe gyin shalat ai hte, gelatin empty capsules ni a ngang grin ai lam hpe sawk sagawn ai lam ni gaw, grau nna gram lajang ai hte hpaji rawng wa nna, shinggyim hkamja lam hpe grau nna madi shadaw ya na re. Empty capsule ni hta ra sharawng ai lam ni nga yang, KornacCaps hpe matut mahkai na matu hkap tau la ga.
